Study of the phytoremediation potential of native plant species identified in an area contaminated by volatile organic compounds: a systematic review.

Phytoremediation is a process that uses plants in situ to promote remediation of environments contaminated by organic or inorganic compounds. Phytoremediating species develop methods such as phytoextraction, rhizofiltration, phytodegradation, and phytovolatilization, which can manifest themselves individually or together in a single plant. This study aims to evaluate, through a systematic review, the potential phytoremediation techniques of the genera Syagrus (Mart.), Nephrolepis, Cyperus (L.), Mimosa (L.), Schinus (L.), Brachiaria, and Eryngium (L.) found in a humid area of Rio Grande do Sul, Brazil. The genera that presented significant numbers in the databases consulted were Cyperus and Brachiaria, followed by Nephrolepis. The first two are considered the most promising for phytoremediation processes. The other genera mentioned obtained favorable results for organic contaminants. The studies around these genera are still recent. It is necessary, in research, to highlight which phytoremediation processes the plants exert in relation to the contaminant of the place. In addition, priority should be given to native species that can establish themselves in the environment and that would not unbalance and harm the surrounding biota and ecosystem.

The research presents a survey of two decades in four multidisciplinary and international databases, identifying the limitation of research related to volatile and semi-volatile organic compounds, as well as contributing to the identification of native plant species that perform phytoremediation mechanisms.

Impact of coffee biochar on carbon, microbial biomass and enzyme activities of a sandy soil cultivated with bean.

Biochar has been used to reuse the agro-industrial wastes and improve soil quality. Several studies have been carried out to show the impact of biochar on physical and chemical soil attributes. However, there are still gaps regarding the effects on as microbial biomass and enzymatic activities that are important to determine sensitive indicators to evaluate changes in management practices. The objective of this study was to assess the effect of two biochars on the chemical, microbial biomass carbon, and the enzymatic activities in an Entisol cultivated with bean. We evaluate two types of coffee biochar: ground and husks, four doses (4, 8, 12, and 16 Mg ha-1) and control. All treatments received organic fertilization with cow manure. Husks biochar increase the soil pH, Ca, and K, also contributing to the reduction of toxic aluminum contents and raising the concentrations of P labile. The treatments that received ground biochar showed higher soil organic carbon, microbial biomass, ß-glucosidase, and fluorescein diacetate. Biochar produced from coffee residues increased sandy soil quality. We showed the first report on the beneficial impact of coffee biochar on enzymatic and microbiological quality of sandy soil cultivated with the bean.

Nanopartículas de plata en el tratamiento de la micosis asociada al pie diabético / Silver nanoparticles to treat mycosis associated with diabetic foot / Nanopartículas de prata no tratamento da micose associada ao pé diabético

Resumen: Una proporción importante de infecciones en el pie diabético consisten en onicomicosis y tinea pedis, problema común en el pie, amenazante de la viabilidad del tejido que puede provocar infecciones bacterianas secundarias. Requieren períodos prolongados de tratamiento antimicótico con alta tasas de recaídas y reinfección. Diversos estudios han mostrado la seguridad y eficacia de las nanopartículas de plata (NP Ag) como agente antimicrobiano. Realizamos un estudio donde se evaluó el tratamiento con NP Ag en dermatomicosis del pie de pacientes diabéticos. Método: estudio piloto, abierto, prospectivo, randomizado y controlado en pacientes que asisten a una policlínica de pie diabético. Dieciocho pacientes cumplieron con los criterios de inclusión conformándose dos grupos homogéneos. Ambos grupos recibieron tratamiento estándar que consistió en antimicótico tópico y desbastado mecánico. El grupo intervención utilizó un textil (medias) confeccionadas con hilos con NP Ag. Se realizó control clínico y microbiológico hasta las 12 semanas. Se evaluó el porcentaje de remisión y el tiempo hasta alcanzar el mismo. Resultados: predominó la onicomicosis y el germen Trichophyton rubrum. En el grupo intervención se logró un mayor porcentaje de remisión de lesiones y en un tiempo menor que el grupo control. Conclusiones: el uso de medias confeccionadas con hilos de NP Ag se asoció con una mayor probabilidad de curación completa en un período de 12 semanas a pesar de que el número de pacientes no permitió llegar al nivel de significación estadística, pudiendo contribuir a la prevención de infecciones o úlceras suplementarias en el pie diabético.

Summary: Onychomycosis and tinea pedis represent a significant proportion of infections in the diabetic foot, a common foot problem, and they constitute a threat to the viability of tissues that may provoke secondary bacterial infections. To combat them, antifungal treatments are required for long periods of time, the rates of relapse and reinfection being high. Several studies have proved the safety and effectiveness of silver nano particles (NP Ag) as an antimicrobial agent. A study was conducted to assess nanoparticle agents for foot dermatomycosis in diabetic patients. Method: pilot, open, prospective randomized and controlled study in patients who are assisted in a diabetic foot policlinic. 18 patients complied with the inclusion criteria and two homogeneous groups were formed. Both groups received standard treatment consisting in topic antifungal and mechanical roughing. The intervention groups used a textile (stockings) made with silver nanoparticle threads. Clinical and microbiological control was made during 12 weeks, also assessing the remission percentage and the time it took to achieve it. Resultados: onychomycosis and trichophyton rubrum prevailed. The intervention group showed a greater percentage of remission of lesions in a period of time that was shorter than that of the control group. Conclusions: the use of stockings made with NP Ag threads was associated with a greater probability of complete healing, in a 12-week period, despite the fact that the number of patients was not statistically significant. This could contribute to the prevention of supplementary infections or ulcers in the diabetic foot.

Resumo: Uma proporção significativa de infecções do pé diabético consiste em onicomicose e Tinea pedis, um problema comum nos pés que ameaça a viabilidade do tecido e pode causar infecções bacterianas secundárias. Requerem períodos prolongados de tratamento antifúngico com altas taxas de recidiva e reinfecção. Vários estudos têm demonstrado a segurança e a eficácia das nanopartículas de prata (NP Ag) como agente antimicrobiano. Realizamos um estudo onde o tratamento com NP Ag foi avaliado na dermatomicose do pé de pacientes diabéticos. Método: estudo piloto, aberto, prospectivo, randomizado e controlado em pacientes atendidos em uma policlínica de pé diabético. Dezoito pacientes preencheram os critérios de inclusão, formando dois grupos homogêneos. Ambos os grupos receberam tratamento padrão que consiste em antifúngico tópico e moagem mecânica. O grupo intervenção utilizou um tecido (meias) confeccionado com fios NP Ag. O controle clínico e microbiológico foi realizado até 12 semanas. A porcentagem de remissão e o tempo para alcançá-la foram avaliados. Resultados: predominaram a onicomicose e o germe Trichophyton rubrum. No grupo intervenção, obteve-se maior percentual de remissão das lesões e em menor tempo que o grupo controle. Conclusões: o uso de meias confeccionadas com fios NP Ag esteve associado a uma maior probabilidade de cura completa, no período de 12 semanas, apesar do número de pacientes não permitir atingir o nível de significância estatística, podendo contribuir para a prevenção de infecções ou úlceras adicionais no pé diabético.

Predicting dimensions of clinical-functional conditions and cognition in the elderly.

OBJECTIVE: To evaluate the predictive dimensions of clinical-functional conditions and the cognitive capacity of elderly people living at home. METHOD: Cross-sectional, population-based, analytical, quantitative study was utilized. For data collection, an instrument with sociodemographic and behavioral variables, the Functional Clinical Vulnerability Index; and, to assess cognition, the Mini-Mental State Examination (MMSE) was used. Descriptive analyzes and statistical tests were conducted. RESULTS: 305 elderly subjects, living at home, in urban and rural areas participated in the study. They were classified as robust (71.8%), pre-frail (22%) and frail (6.2%). As for cognition, 24.9% of them had cognitive impairment. It was shown that cognitive impairment predicts the development of functional disability. CONCLUSION: It is considered that health professionals should both act in order to maintain the functional and cognitive conditions of the robust and pre-frail elderly people and pay attention to the rehabilitation of the disabilities installed in those elderly people who are in a situation of frailty.

Predicting dimensions of clinical-functional conditions and cognition in the elderly / Dimensiones indicadoras de las condiciones clínico-funcionales y cognición en ancianos / Dimensões preditoras das condições clínico-funcionais e cognição em idosos

ABSTRACT Objective: To evaluate the predictive dimensions of clinical-functional conditions and the cognitive capacity of elderly people living at home. Method: Cross-sectional, population-based, analytical, quantitative study was utilized. For data collection, an instrument with sociodemographic and behavioral variables, the Functional Clinical Vulnerability Index; and, to assess cognition, the Mini-Mental State Examination (MMSE) was used. Descriptive analyzes and statistical tests were conducted. Results: 305 elderly subjects, living at home, in urban and rural areas participated in the study. They were classified as robust (71.8%), pre-frail (22%) and frail (6.2%). As for cognition, 24.9% of them had cognitive impairment. It was shown that cognitive impairment predicts the development of functional disability. Conclusion: It is considered that health professionals should both act in order to maintain the functional and cognitive conditions of the robust and pre-frail elderly people and pay attention to the rehabilitation of the disabilities installed in those elderly people who are in a situation of frailty.

RESUMEN Objetivo: Evaluar las dimensiones indicadoras de las condiciones clínico-funcionales y la capacidad cognitiva de ancianos residentes en el domicilio. Método: Estudio transversal de base poblacional, analítico, cuantitativo. Para recogida de datos, se ha utilizado: instrumento con variables sociodemográficas y comportamentales, el Índice de Vulnerabilidad Clínico Funcional; y, para evaluar la cognición, el Mini Examen del Estado Mental. Han sido conducidos análisis descriptivos y test estadísticos. Resultados: Participaron del estudio, 305 ancianos, residentes en el domicilio, en área urbana y rural. Ellos se clasificaron en robustos (71,8%), pre-frágiles (22%) y frágiles (6,2%). En cuanto a la cognición, 24,9% de ellos presentaron déficit cognitivo. Se ha evidenciado que el comprometimiento cognitivo predice el desarrollo de incapacidad funcional. Conclusión: Se considera que los profesionales de salud deben tanto actuar en el sentido de la manutención de las condiciones funcionales y cognitivas de los ancianos robustos y pre-frágiles cuanto atentar para la rehabilitación de las incapacidades instaladas en aquellas personas ancianas que se encuentran en situación de fragilidad.

RESUMO Objetivo: Avaliar as dimensões preditoras das condições clínico-funcionais e a capacidade cognitiva de idosos residentes no domicílio. Métodos: Estudo transversal de base populacional, analítico, quantitativo. Para coleta de dados, utilizou-se: instrumento com variáveis sociodemográficas e comportamentais, o Índice de Vulnerabilidade Clínico Funcional; e, para avaliar a cognição, o Mini Exame do Estado Mental. Foram conduzidas análises descritivas e testes estatísticos. Resultados: Participaram do estudo, 305 idosos, residentes no domicílio, em área urbana e rural. Eles classificaram-se em robustos (71,8%), pré-frágeis (22%) e frágeis (6,2%). Quanto à cognição, 24,9% deles apresentaram déficit cognitivo. Evidenciou-se que o comprometimento cognitivo prediz o desenvolvimento de incapacidade funcional. Conclusão: Considera-se que os profissionais de saúde devem tanto atuar no sentido da manutenção das condições funcionais e cognitivas dos idosos robustos e pré-frágeis quanto atentar para a reabilitação das incapacidades instaladas naquelas pessoas idosas que se encontram em situação de fragilidade.

Resultados a corto plazo del tratamiento con 131I en el bocio multinodular: valor adicional de la estimulación previa con rhTSH / Short-term results of treatment with 131I in multinodular goiter: additional value of previus stimulation with Recombinant human thyrotropin

OBJETIVO: El yodo radiactivo (131I) es una opción terapeútica segura y eficaz cuando se utiliza solo o con la estimulación previa de TSH recombinante humana (rhTSH) en el tratamiento del bocio multinodular (BMN). En espera de ensayos clínicos que determinen la dosis óptima, demuestren seguridad y confirmen la eficacia, diferentes protocolos se utilizan para aplicar la dosis de 131I. Analizamos la respuesta al tratamiento con una dosis calculada por protocolo mixto (dosis fijas y cálculo por porcentaje de captación) en pacientes con BMN toxico y no toxico en nuestro hospital, en el periodo 2010-2013. MATERIALES Y MÉTODOS: Estudio prospectivo en pacientes con BMN no quirúrgico (BMNNQ) que requerían reducción del volumen glandular y/o tratamiento del hipertiroidismo. Se evaluaron 134 pacientes, 14 cumplieron con los criterios de inclusión (13mujeres) de edad media 71.08 años. Un grupo con BMN toxico, otro grupo con BMN no toxico, un tercer grupo con BMN no toxico estimulado con 0,1 mg de rhTSH previo a la dosis. Se evaluó, función tiroidea, captación tiroidea de 99ᵐTc, volumen tiroideo y síntomas compresivos. Se siguió a los pacientes durante 12 meses. RESULTADOS: Se aplicaron dosis entre 15 y 30 mCi de 131I. Remitió el hipertiroidismo en 6 de 7 pacientes. Hubo una reducción del volumen glandular (p<0.01).Los pacientes con estímulo de 0,1 mg rhTSH, aumentaron el porcentaje de captación de 99ᵐTc a las 24 h en un 32.43±10.61 permitiendo aplicar menor dosis de 131I. La tasa de aparición de hipotiroidismo fue de 7.41 por cada 100 pacientes.mes, mayor en pacientes con BMN toxico tratados con dosis bajas (p-=0.03). Hubo una mejoría subjetiva de la clínica compresiva en todos los pacientes. No hubo eventos adversos. CONCLUSIONES: Una dosis de 131I calculada por protocolo mixto es efectiva y segura para la reducción del volumen glandular y control del hipertiroidismo asociado. La estimulación con rhTSH logra el mismo efecto con una menor dosis administrada.

OBJECTIVE: Radioactive iodine (131I) is a safe and effective therapeutic option when used alone or with prior stimulation of recombinant human Thyrotropin (rhTSH) in the treatment of multinodular goiter (MNG). In absence of clinical trials that determine the optimal dose, demonstrate safety and confirm efficacy, different protocols are used to apply the dose of 131I. We analyze the response to treatment with a dose calculated by mixed protocol (fixed doses and calculation by percentage of uptake) in patients with toxic and non-toxic MNG in our hospital, in the period 2010-2013. MATERIALS AND METHODS: Prospective study in patients with non-surgical MNG that required glandular volume reduction and / or treatment of hyperthyroidism. 134 patients were evaluated, 14 met the inclusion criteria (13 women) of average age 71.08 years. One group with toxic MNG, another group with non-toxic MNG and a third with non-toxic multinodular goiter stimulated with 0.1 mg of rhTSH prior to the dose. Patients were followed for 12 months. Upon following, we assessed Thyroid function, 99ᵐTc thyroid uptake, thyroid volume and compressive symptoms. RESULTS: Doses between 15 and 30 mCi of 131I were applied. We observed hyperthyroidism remission in 6 of 7 patients. There was a reduction in glandular volume (p <0.01) considering all patients. Patients with a stimulus of 0.1 mg rhTSH, increased the percentage of uptake of 99ᵐTc at 24 h by 32.43 ± 10.61, allowing a lower dose of 131I to be applied. The rate of onset of hypothyroidism was 7.41 per 100 patients-month, and was higher in patients with toxic MNG treated with low doses (p = 0.03). There was a subjective improvement of the compression clinic in all patients. No adverse events were observed. CONCLUSIONS: A dose of 131I calculated by a mixed protocol is effective and safe for achieving glandular volume reduction and associated hyperthyroidism control. Stimulation with rhTSH produces the same effect with a lower administered dose.

Transferência como resistência: discussão a partir da experiência de supervisão / Transference as resistance: discussion based on the supervision experience / Transferencia como resistencia: discussion basado en laexperiencia de la supervision

Este artigo apresenta conceitos importantes para a prática psicanalítica e aborda como a transferência e a resistência se manifestam no contexto clínico. Objetiva demonstrar como uma dá lugar à outra a partir da análise de um recorte de uma história clínica marcada por uma transferência de resistência e supervisão da profissional, utilizando a psicanálise como arcabouço teórico. A importância da supervisão é enfatizada, juntamente com a análise pessoal da profissional, para manejar a transferência e alcançar a eficácia clínica. Tal ênfase deve-se às dificuldades que principiantes em psicanálise lidam com conteúdos inconscientes que emergem de seus pacientes, sobretudo relacionados à sexualidade. Para contribuir com o tema, são sugeridos estudos de caso de neurose de transferência.

This article presents important concepts for psychoanalytic practice and discusses how transference and resistance are manifested in the clinical context. It aims to demonstrate how one supplants the other from the analysis of an extract of a clinical history marked by a transference of resistance and supervision of a professional, using psychoanalysis as a framework. The importance of supervision is emphasized, together with the personal analysis of the professional, to conduct the transference and achieve clinical efficiency. Such emphasis is due to difficulties that beginners in psychoanalysis manage the unconscious content that emerges from their patients, mainly related to sexuality. To contribute to the theme, case studies of transference neurosis are suggested.

Este artículo presenta conceptos importantes para la práctica psicoanalítica y analiza cómo la transferencia y la resistencia se manifiestan en el contexto clínico. Su objetivo es demostrar cómo uno sustituye al otro del análisis de un extracto de una historia clínica marcada por una transferencia de resistencia y supervisión de un profesional, utilizando el psicoanálisis como marco. Se hace hincapié en la importancia de la supervisión, junto con el análisis personal del profesional, para llevar a cabo la transferencia y lograrla eficienciaclínica. Tal énfasis se debe a las dificultades que los principiantes en el psicoanálisis manejan el contenido inconsciente que emergede sus pacientes, principalmente relacionados con la sexualidad. Para contribuir al tema, se sugieren estudios de caso de neurosis de transferencia.

Chemical constituents of Cochlospermum regium (Schrank) Pilg. root and its antioxidant, antidiabetic, antiglycation, and anticholinesterase effects in Wistar rats.

The main physiological consequence of diabetes mellitus is chronic hyperglycemia. This condition is related to the formation of free radicals including advanced glycation end products (AGES) and to an increase in inflammatory processes. Cochlospermum regium (Schrank) Pilg., part of the Bixaceae family, is a cerrado plant known for its anti-inflammatory effects. The objectives of this study were to analyze the constituent compounds of C. regium roots and to evaluate the antioxidant, antiglycation, antidiabetic, and anticholinergic effects of its hydromethanolic extract through in vitro and in vivo experimental models. The presence of phenols, flavonoids, condensed tannins, and flavonols was analyzed by liquid chromatography - photodiode array (LC/PDA) analysis. Whereas antioxidant activity was investigated via DPPH, ABTS, ß-carotene/linoleic acid, and malondialdehyde colorimetric assays. Inhibition of AGEs was examined via a bovine serum albumin system whose glycosylating agent was glucose. Antidiabetic potential was examined in normoglycemic Wistar rats that received glucose overload, in alloxan-induced diabetic rats, and in rats that received a hyperglycemic diet. Disaccharidase inhibition was assessed using in vitro and in vivo methods, as was acetylcholinesterase (AChE) inhibition in brain structures. The hydromethanolic extract (CRHE) possessed a high concentration of phenolic compounds and showed antioxidant effects. The LC-DAD results revealed that CRHE contained a high concentration of phenolic acids and the majority was gallic acid. Treatment with CRHE caused significant inhibition of AGE formation. The oral glucose tolerance test (OGTT) in normoglycemic animals showed a reduction in blood glucose levels after treatment with 100 mg/kg CHRE, accompanied by an increase in hepatic glycogen content. There was also a significant reduction in the fasting glucose levels of alloxan-induced diabetic animals after 7 days of treatment with daily doses of 100 mg/kg. After 14 weeks of hyperglycemic diet, the last four or which were combined with 100 mg/kg CRHE treatment, there was a decrease in blood triglyceride levels. There was also a statistically significant decrease in the enzymatic activity of maltase, lactase and sucrase. The results demonstrate that oral administration of 30 and 100 mg/kg CRHE inhibited AChE activity in different brain structures. Thus, the extract of C. regium showed promising antioxidant, antiglycation, and antidiabetic effects that may be related to its high phenolic content.

Social representations of anorexia among university students and risk factors: possible relations / Representações sociais da anorexia entre estudantes universitárias e fatores de risco: possíveis relações / Representaciones sociales de la anorexia entre estudiantes universitarios y factores de riesgo: posibles relaciones

Anorexia is a serious disease, characterized by a distorted body image that leads to extreme behavior. It mainly affects young women. This study sought to identify the social representations of anorexia and the presence of risk factors for its development among female students from different university courses. It sought to establish relationships between anorexia risk factors, body mass index, study area, body satisfaction and social representations. A questionnaire composed by the EAT-26, scale of body silhouettes and open questions about what students knew about anorexia was applied. The data were subjected to statistical and lexicographic analysis. 29% of the students presented risk factors for anorexia. Increased BMI and body dissatisfaction are related to the presence of risk factors. Social representations of anorexia demonstrate the characterization of the disease, very close to scientific knowledge.

A anorexia é uma doença grave, caracterizada por uma imagem corporal distorcida que leva a comportamentos extremos. Acomete principalmente jovens mulheres. Este estudo procurou identificar as representações sociais da anorexia e a presença de fator de risco para seu desenvolvimento entre 100 estudantes do sexo feminino de diferentes cursos superiores. Buscou estabelecer relações e entre fator de risco para anorexia, índice de massa corporal, curso superior e satisfação corporal e representações sociais. Foi aplicado um questionário composto pelo EAT-26, escala de silhuetas corporais e questões abertas sobre o que as estudantes sabiam sobre a anorexia. Os dados foram alvo de análises estatísticas e lexicográficas. 29% das estudantes apresentaram fator de risco para anorexia. IMC aumentado e insatisfação corporal estão relacionados à presença de fator de risco. As representações sociais da anorexia demonstram a caracterização da doença, muito próxima do conhecimento científico.

Anorexia es una enfermedad grave, caracterizada por una imagen distorsionada del cuerpo que conduce a un comportamiento extremo. Afecta principalmente las mujeres jóvenes. Este estudio busco identificar las representaciones sociales de la anorexia y la presencia de factores de riesgo para su desarrollo entre 100 mujeres estudiantes de diferentes carreras universitarias. Y buscado establecer relaciones entre los factores de riesgo para la anorexia, el índice de masa corporal, área de estudio, la satisfacción del cuerpo y las representaciones sociales. Se aplicó el cuestionario compuesto de la escala EAT-26, de siluetas corporales y preguntas abiertas sobre lo que los estudiantes sabían sobre la anorexia. los datos fueron sometidos a análisis estadística y lexicográfica. 29% de los estudiantes presenta factores de riesgo para la anorexia. El aumento de IMC y la insatisfacción corporal se relaciona con la presencia de factores de riesgo. Representaciones sociales de la anorexia demuestra la caracterización de la enfermedad, muy cerca de los conocimientos científicos.